How to identify and treat dvs syndrome in children

The syndrome of disseminated intravascular coagulation is a complex process that often accompanies many pathologies. It is characterized by the emergence of ubiquitous blood clotting in the channel of circulation and blockade of microcirculation, hypoxia in the tissues and disruption of the organs.

DIC syndrome in children due to increased blood viscosity properties slows the normal flow of blood. When passing through small capillaries, the blood is stratified, plasma and red blood cells are released. At the child such process is shown by painting of a skin by a marble pattern. Subsequently, peripheral blood is impoverished, anemia and intoxication develop.

Causes of pathology

The main factors contributing to the development of DIC syndrome, correlate with the factors of the fetal development process. With a high probability the doctor can predict the onset of the syndrome in newborns when fixing a premature detachment of the placenta or intrauterine gestational lesion.

As the DIC grows, the child's syndrome is formed when the body is infected with inflammatory and infectious diseases. The provoking factors include rhesus conflict with the mother, malfunctioning of the liver and kidneys, transfusion of the blood of an unsuitable group.

Symptoms of the disease

DIC syndrome in newborns or in children at an older age is a serious complication of various diseases of the mother in the perinatal period. In newborns, the pathology often takes a lightning or acute form and has four stages of development:

• The stage of hypercoagulability.
• Stage of hypocoagulation.
• The stage is fibrinolytic.
• Recovery phase.

In fetus or in a newborn, DIC syndrome often develops when the fetus is damaged or tissue necrosis develops, which releases tissue thromboplastin into the bloodstream of the mother and fetus. Violation of tissue integrity occurs in the case of detachment of the normally located placenta or the death of one of the two fruits.

The acute course of the pathology is characterized by the fact that the symptoms of dvs syndrome have been occurring for several hours. The acute form manifests itself in sepsis, when getting extensive burns or frostbites, with prolonged squeezing syndrome, etc.

Most patients have a disruption to the respiratory system, which is manifested by severe shortness of breath. In 60 - 70% of cases kidney failure, soreness in the lower back, urine volume decreases, it reveals the presence of erythrocytes, protein, and cylinders.

Diagnosis of

The methods and volumes of laboratory tests for the development of ICE syndrome depend on the conditions under which treatment is performed.

Clinical data are determined in accordance with two factors:

1. Severity of blood flow disturbance in the course of microcirculation of various organs, which explains their dysfunction.
2. Degree of distribution and intensity of hemorrhage development. In addition, bleeding affects the functioning of the internal organs, changing the symptoms of the disease.

Infringements of microcirculation can provoke insufficiency of functioning of systems and organs depending on a place of defeat and prevalence. This process is manifested as follows:

• Symptoms of abnormal peripheral blood flow are skin blanching, a marble pattern on the skin, brush strokes and feet.
• The onset of an acute form of kidney failure.
• Acute form of respiratory failure.
• Acute abnormalities of blood flow in the brain.
• Hepatorenal syndrome. Acute adrenal insufficiency.

Treatment of pathology

The organization of treatment of DIC syndrome involves the elimination of the cause of its development. Subsequently, specialists base therapy on getting rid of intoxication, normalization of blood flow and elimination of complications in the development of such. Much attention should be given to the rheological characteristics of blood in case of infection of the body with flu and cold pathologies, which are supplemented by a strong increase in body temperature. This can lead to the emergence of a massive ICE syndrome in the body of infants or toddlers.

The process of treating this pathology is a complex clinical problem that requires an integrated approach. It is important to adhere to the following rules and principles of therapy:

• Treatment of an acute form of pathology should begin immediately after taking blood for tests. And only with chronic forms is permitted to conduct a preliminary study.
• The physician should immediately take action to eliminate the etiological factors of DIC syndrome and the effects that can aggravate its course. First of all, the elimination of the shock and intoxication is organized.
• During the treatment it is required to evaluate the clinical picture without fail, taking into account the potential danger of treatment, which can only exacerbate the manifestations of DIC syndrome.

The main components of the complex treatment are:

1. Elimination of the causes of the disease and pathogenetic therapy of primary pathology.
2. An anti-shock treatment and maintenance of the required composition and volume of blood circulating in blood vessels.
3. Inkjet infusion.
4. Heparinotherapy.
5. Introduction of inhibitors as a function of indications.
6. Previously, the use of drugs that improve microcirculation and reduce the loss of blood platelet blood.
7. Substitution of lost red blood cells.
8. With severe hypocoagulation, severe bleeding and pronounced thrombocytopenia, transfusions of platelet concentrates are produced, as well as the introduction of large Doctors kontrikal.
9. Organization of local hemostasis with a fibrogastroscope.