What are the causes of systemic lupus erythematosus? How to cure it
Often, patients who suffer from systemic lupus erythematosus are wondering what caused this severe systemic connective tissue disease and whether it is possible to somehow cure this disease.
Causes and provoking factors
Even the numerous long-term studies conducted by domestic and foreign rheumatologists failed to answer the question of why lupus erythematosus develops - the causes of the disease are closely interrelated with such an insufficiently studied field of physiology as the regulation of the immune response in the body.
Under the influence of viral infections, excessive sun or ultraviolet insolation, changes in the hormonal background, stresses( both physical and psychological), the normal course of immunity reactions is disrupted in patients and antibodies to the body's own tissues begin to develop.
First and foremost, autoimmune antibodies arise to connective tissue cells - resulting in inflammation with a pronounced immune and allergic component.
In the process of development of a pathological reaction, the body's antibodies are produced to the cells proper - the production of specific autoimmune antibodies to tissues explains why one or another organ is affected.
Lupus erythematosus is very insidious - it can persist for a long time in the body in a chronic form and manifest itself only by skin lesions and minor changes in the organs of the musculoskeletal system.
At the same time, immune abnormalities continue to accumulate, which can initiate autoimmune inflammation in virtually any organ in the human body.
Is lupus erythematous?
In case the patient develops lupus erythematosus - the causes of the disease can be very different, but the conducted studies have proved the answer to the question - whether red lupus is contagious or not, can be given unambiguous.
The disease is not contagious, it is not transmitted from person to person, and in a particular patient the pathological process is not caused by some particular pathogen, but under the influence of some of the provoking factors.
As a result, the normal mechanism of the immune response changes, and the body begins to perceive its own cells as foreign, begins to fight them in every way, going back to destroy.
As a result, the scar tissue develops on the site of the destroyed cells, which causes the development of the deficiency of the function of the affected organ( renal, respiratory, cardiovascular, hepatic), and it is impossible to guess which organ will be affected the next time the inflammatory process is activated.
How is the disease transmitted
It is proved that one can not answer unequivocally the question - how is lupus transmitted. In this disease, not autoimmune disease itself is transmitted, but a predisposition to it, and when the disease develops among members of the same family, the risk of lupus itself or of some diseases developing along the same mechanism( systemic scleroderma, Sjogren's syndrome) is much higher than inpopulation as a whole.
Women suffer from lupus much more often than men - women represent 90% of adult patients( only in infancy, girls are more likely to have SVCs three times more often than boys).
This fact indicates the influence of the hormonal profile on the course of the disease - this is also evidenced by the development of exacerbations of lupus in women after childbirth, abortion.
This is why patients are advised to consider the issues of pregnancy planning and the use of hormonal contraceptives to prevent it, the sex hormones themselves can activate the autoimmune process in the body, in addition, they can increase the likelihood of complications of the disease( vascular thrombosis, vasculitis).
Treatment of the disease should be carried out by a qualified rheumatologist who will monitor the patient's condition and the body's response to the prescribed treatment.