Treatment of fatty liver hepatosis with drugs
Fatty liver hepatosis is a noninflammatory disorder characterized by impaired metabolism of fats in the hepatic cells followed by their dystrophy.
The causes of fatty hepatosis can be:
- Obesity
- Drug administration: tetracycline antibiotics, glucocorticosteroids, antidepressants, nonsteroidal anti-inflammatory drugs
- Chronic gastrointestinal pathology, accompanied by impaired absorption of nutrients: pancreatitis, colitis, enteritis
- Rapid uncontrolled weight loss
- Hereditary metabolic diseases
- Diabetes mellitus type 2
- Alcoholism
- Toxic defeat of the stoveneither poisonous fungi nor pesticides
Classification of the disease
According to the morphological pattern of fatty hepatosis is classified:
- Fatty hepatosis of the 0 degree, when several single hepatocytes are affected
- Fatty hepatosis of the 1st degree - changes are more pronounced, more than half of the hepatic cells
- are affected. Hereditary hepatosis of the 2nd degree is the dystrophy of allhepatocytes without extracellular obesity
- Fatty hepatosis of the third degree is the most severe lesion, accompanied by the regeneration of hepatic cells in a large numberfatty cysts and extracellular obesity
Clinical picture
Symptoms of fatty hepatosis are diverse and quite nonspecific. The disease can be hidden for years, and can give a violent clinical picture. Most often, patients complain of minor pain in the right upper quadrant, dyspeptic phenomena in the form of chronic diarrhea or constipation, general fatigue.
There is less fatty hepatosis accompanied by a sharp pain syndrome, weight loss, bloating, itching and jaundice. Most often diagnosed fatty hepatosis by ultrasound with subsequent confirmation of the diagnosis of puncture liver biopsy.
How to treat fatty liver hepatosis?
If the treatment of fatty liver hepatosis is started in time, then the prognosis for the disease is quite favorable. And at the same time, there is no specific treatment for fatty hepatosis. The whole strategy is to:
- eliminate possible factors of the disease
- lifestyle and nutrition correction
- taking drugs that improve metabolism in hepatocytes and protect them from damaging factors
The first thing that patients must adhere to when fat liver hepatosis is a diet. The food should be balanced, with the optimal content of proteins and carbohydrates, but with a reduced fat potential. Products whose use in the treatment of fatty hepatosis should be excluded:
- Alcohol
- Sweets: sweets, chocolate
- Fatty meat and dairy products with a high percentage of fat
- White pastries, pasta, flour products
- Mayonnaise, margarine
- Salo, fat
Useful products:
- All vegetables and fruits
- Porridge: buckwheat, oatmeal, corn, brown rice
- Fish and seafood
- Low-fat meat types
- Low-fat cottage cheese, kefir, yoghurt
In addition,the detection method of frying food. It is better to bake, boil or steam. You should also drink at least 2-2, 5 liters of liquid in the form of unsweetened compotes and fruit drinks, green tea or just pure drinking water.
Treatment of fatty liver hepatosis with drugs is aimed at improving metabolism in hepatocytes, increasing their resistance to external damaging factors. For this, several groups of drugs are used:
- Medicines containing in their composition essential phospholipids: Essentiale, Essler forte, phosphoglue. The therapeutic effect is associated with hepatoprotective action. Phospholipids, being a part of cell membranes, can stimulate the restoration of damaged liver cells, activation of the metabolic process in them.
Thus, the liver increases resistance and the ability to detoxify harmful substances. Such drugs should be taken for several months, followed by therapy in maintenance doses very long.
- Preparations related to the group of sulfoamino acids: methionine, heptral, taurine. The mechanism of their action is associated with the stimulation of the production of their own phospholipids and antioxidant properties.
In addition, these drugs improve the hepatic blood flow, promote the removal of excess fats from cells, reduce the viscosity of bile and correct the carbohydrate metabolism. The course of treatment with sulfoamino acids usually lasts one to two months.
- Medicines based on extracts from plants: hofitol, carpel, livestock 52. Often these drugs have an unidentified mechanism of action. It is possible that their effect is associated with complexes of biologically active substances, vitamins that possess antioxidant and hepatoprotective properties.
For the treatment of fatty liver hepatosis, drugs are selected depending on the severity of the disease, its duration and clinical picture. The intake of medications is sometimes quite effectively supplemented with the treatment of fatty hepatosis with folk remedies.
Turmeric, milk thistle, dandelion root, nettle, sorrel curly, artichoke, birch leaves, medicinal chamomile in the form of broths and infusions normalize the production and outflow of bile, regulate the exchange of sugar and fats, antioxidant and membrane-stabilizing action. To avoid the development of complications, the treatment of fatty hepatosis should be carried out strictly under medical supervision.