Huntington's disease - features of the course and treatment of severe disease
One of the most serious diseases today is Huntington's disease. This is a hereditary pathology of the brain. It is characterized by the articulation of disorders of the human psyche with choreic hyperkinesis.
This disease is rare. According to statistical data, the prevalence is approximately one case to ten thousand souls of the population.
Strange and insidious, Huntington's disease affects both small children and elderly people. But most often the first manifestations appear in a patient aged 28-50 years.
Features of the disease
For several centuries, medical luminaries have tried to get to the bottom of this strange and rather terrible genetic defect. Today it is believed that the basis of Huntington's disease is an increase in the length of a triplet genetic code. Against this background, a pathological protein appears in the nerve cells and develops. Over time, metabolic disorder progresses within the cell, leading to biochemical disorders in the human brain.
Huntington's disease is inherited by children from parents who are carriers of the mutated gene. Doctors say that the disease is equally transmitted to children of male and female.
Often the first signs of Huntington's chorea arise even when a person grows up and gets a family. The average age of the first symptoms is twenty-eight to thirty-five years. The most terrible thing is that the mutated gene by this time can already "settle" in the body of one of the children of the patient.
In some cases, the symptoms of the disease manifest earlier, in adolescence.
Huntington's disease often ends in the death of the patient. But the lethal outcome does not come as a result of increased symptoms, but against the background of accompanying anomalies.
Approximately twenty percent of patients commit suicide. This occurs in the tenth-twentieth year after the appearance of the first signs of Huntington's chorea.
Features of the manifestation
Huntington's disease manifests itself gradually. The first stage is characterized by only minor changes in the personality of the patient. Also, physical skills and cognitive abilities of the patient are subject to some transformation.
Disease Horeignon's chorea in the initial stage is manifested by disordered movements, which the patient is unable to control. In the first stages, the chorea manifests itself in the form:
- Some movements that do not have logical sequence and completion.
- Increasing anxiety.
- Deceleration of spasmodic movements of the organs of vision.
- Coordination failures.
Some patients move swiftly, others - on the contrary, seem to outsiders to somewhat "inhibited".The speech of the patient loses its intelligibility, and after losing functions that involve muscle control, the stage of grimacing begins. Against this background, the patient has serious difficulties with swallowing and chewing. In connection with the rapid movement of the organs of vision, a person begins to suffer from insomnia and other sleep disorders.
As the pathological condition progresses, there is a violation of abstract thinking. Gradually the patient loses the ability to plan his actions. Often, he becomes slovenly, ignores the rules that he tried to adhere to earlier. An adequate assessment of one's own actions also disappears.
The next step is to reduce memory.
Against the backdrop of a pathological memory loss, the patient suffers from:
- depressive manifestations;
- panic disorder;
A person becomes self-centered, super-anxious and often aggressive. Over time, he has problems with the recognition of his loved ones. Depending on the pathological inclinations of the patient, his vices are amplified. The combination of grimacing, aggressiveness and a tendency to completely wild acts and forced people who lived centuries ago, to consider people with Huntington's disease possessed by the devil.
Duration of the disease
Horea Huntington on average takes about fifteen years. If the symptoms appeared before reaching a man of twenty-five years of age, then the pathology progresses over 8 years.
Epileptic seizures for this anomaly are not characteristic. In rare cases, they occur at the earliest stages.
During the 4-5th decade, symptoms of progressive choreoarthrosis appear, which is often accompanied by attempts to settle scores with life.
During the course of the disease a person can be assigned a certain group of disabilities. This is due to serious motor and mental disorders.
Diagnosis and treatment
The specialist can make a correct diagnosis based on specific symptoms that disturb the patient. To clarify the diagnosis, the patient is assigned the passage of CT and MRI.In the course of the study, the specialist undertakes to differentiate Huntington's disease with Parkinson's and Wilson's disease.
There is no specific treatment that facilitates the development of a pathological condition, unfortunately, does not exist yet. But in order to suppress hyperkinesis, the doctor can prescribe the administration of neuroleptics.
When the disease is accompanied by a depressed state of the patient, it is prescribed antidepressants. Also, the patient is prescribed psychotherapeutic procedures.Like the article? Share with friends and acquaintances: