Hepatosis in pregnancy - an insidious disease!

Hepatosis is a disease of the liver that occurs as a result of a metabolic disorder and the development of dystrophic changes in liver cells with mildly pronounced inflammatory phenomena.

Normally, during pregnancy, no changes should occur in the liver: neither in size, nor in structure, nor in the level of blood supply. But the function can be severely disrupted, as the liver and bile ducts are under an increased load in consequence of the need to neutralize the products of the vital activity of the child. In addition, by the 12th week, the number of hormones that are produced by the liver increases.

Liver pathologies in the first trimester contribute to the development of toxicoses. Such women should be supervised by a therapist and gynecologist. Hospitalization is necessary when it is necessary to resolve the issue of maintaining pregnancy, in case of exacerbation of liver disease or the emergence of gynecological pathology, 2-3 weeks before childbirth.

Causes of

Hepatosis in pregnancy can occur as a consequence of the following reasons:

• increase in the number of produced sex hormones;
• increased liver load;
• congenital dysfunction of enzymatic systems.

Usually in women with hepatosis, sensitivity to estrogen is increased, and if it increases, cholestasis develops - a violation of the process of formation and extraction of bile, which increases the risk of fetal death by 4 times. And during pregnancy, the production of estrogen increases, so the bile flow in the mother's liver slows down.

If the hepatosis in pregnancy occurs in severe form, then there is a need for emergency delivery, preferably at a period of 38 weeks, if the effect of therapy is positive. If there are no violations in the development of the child, then natural childbirth is possible. A third of pregnant women with this diagnosis had a history of premature birth, allergy( mainly antibacterial drugs), gastrointestinal and endocrine diseases.

Symptoms of hepatosis of pregnant

Like any other disease has hepatosis of pregnant symptoms:

• a large number of elements of bile in the blood;
• appearance of bile acids in the urine;
• deficiency of vitamin K in the body;
• decrease in the amount of bile in the intestine;
• negative effect of bile on liver cells;
• skin itching, worse at night, especially on the hands, legs, forearms, abdomen;
• of jaundice;
• fecal discoloration;
• nausea and a feeling of heaviness;
• loss of appetite;
• fast fatigue;
• enlargement of the liver and gallbladder without painful sensations.

In most cases, the symptoms go away after the birth of the baby and are returned in the next pregnancies. Hepatosis during pregnancy is difficult to diagnose, as the uterus increases, which makes it difficult for palpation, blood biochemistry also does not give reliable results, as during pregnancy many parameters change, and laparoscopy, biopsy and radionuclide scanning are generally prohibited. It is because of the complexity of diagnosis that pregnant women are often hospitalized with an incorrect diagnosis, so it is very important to find a highly qualified specialist to save the life of both the baby and mom.

Typology of the disease

There is acute and chronic hepatosis. Acute occurs after poisoning with toxic or poisonous substances, alcohol or food. Chronic develops gradually due to malnutrition, high cholesterol, excessive consumption of alcohol products, obesity, thyrotoxicosis, diabetes, pancreatitis.

Treatment of

Requires hepatosis of pregnant treatment. Treatment means the elimination of risk factors, otherwise the use of medications will be meaningless.

1. Elimination of factors leading to the onset of hepatosis. Here there can be some difficulties: if alcohol and harmful food can be abandoned, then the influence of harmful factors that are related to the profession is difficult to exclude( you can recommend using protective equipment, detox program, recovery course).
2. Reduction of excess weight and a diet high in protein, reducing the amount of fat intake, taking folic and lipoic acids, vitamin B12.
3. Taking medications that reduce the manifestation of symptoms and the risk of premature birth.

Diet and Nutrition for Hepatosis

A diet for pregnant hepatosis involves the rejection of fried, fatty and spicy food. Nutrition for hepatosis should be five-time, you need to drink at least 1.5 liters of water. You should give up muffins and white bread, you can eat rye, bran bread, unhealthy cookies.

It is good to eat baked and boiled fish, buckwheat and oatmeal, vegetables and greens. In the diet should be a sufficient amount of carbohydrates, proteins and fiber. We will have to give up legumes, radish, sorrel and spinach, rich broths, fatty varieties of meat and fish.