Infectious Toxic Shock: How is it manifested?

Infectious-toxic shock( endotoxic, bacteriostatic, septic, bacterial) - is called an urgent and life-threatening condition, caused by exposure to the human body of living pathogens and their biologically active substances.

Infectious-toxic shock is manifested as a whole complex of pathological reactions in the activity of all organ systems and violation of vital functions: respiration, circulation, blood coagulation.

It can develop against a background of bacterial( anthrax, dysentery, plague, typhoid fever, meningococcal infection), viral( hemorrhagic fever, influenza) infections, and also complicate the course of fungal, spirohegen and rickettsial diseases.

This disease in children and the elderly can also occur against the background of chronic inflammatory diseases caused by bacterioids, aerobacter, Pseudomonas aeruginosa, Klebsiella or proteus.

Symptoms of toxic shock syndrome

The clinical picture of septic shock is characterized by a combination of symptoms of generalized infection and acute circulatory insufficiency. The earliest sign of this life-threatening condition is a sharp rise in body temperature( above 39 degrees C) accompanied by a tremendous chill.

Simultaneously with this there is a strong headache, confusion, motor excitement, vomiting, convulsions.

Currently, clinicians distinguish three phases of the disease:

1. Compensated shock - consciousness is clear, motor anxiety can be noted, feelings of anxiety can arise. The extremities are warm. Breathing is quickened. Tachycardia to 100 - 120 beats per minute.
2. Subcompensated - patients are inhibited, apathetic. The skin is pale, moist and cold to the touch. Many patients have acrocyanosis. The temperature in them is often critically reduced to subnormal values. Dyspnea short. Tachycardia up to 160 beats per minute. Blood pressure is low. The amount of urine is reduced, up to the development of anuria. Violations in the blood coagulation system lead to the appearance of hemorrhages on the skin and mucous membranes, as well as to the occurrence of gastrointestinal bleeding.
3. Decompensated infectious-toxic-patient is in a state of complete prostration. He may have seizures. Some patients may fall into a coma. Shortness of breath increases dramatically. Pronounced total cyanosis. Hypothermia. Arterial blood pressure is sharply reduced and may not be determined. Pulse over 160 beats per minute, threadlike. Anuria.

Symptoms for various diseases

• Hemorrhagic fevers, meningitis - leading to the clinical picture is hemorrhagic syndrome;
• Influenza-toxic shock usually develops against the background of the attachment of any bacterial infection;
• Leptospirosis - occurs at the very beginning of antibiotic therapy and is caused by the mass death of bacteria and the release of their endotoxins into the blood.
• Infectious-toxic shock, arising on the background of the use of tampons by women, is characterized by pain in the throat, the appearance of skin hyperemia and rashes on it.

Emergency care for infectious-toxic shock

Septic shock is an urgent state of the patient that requires immediate medical attention.

Patient with ailment should be laid. If the skin of the lower limbs is cold, then warmers use warmers. Be sure to establish a supply of moistened oxygen and install urinary and venous catheters. Further treatment is carried out under the guidance of a physician.

The main purposes of therapy are:

• Detoxification;
• Restoration of microcirculation;
• Correction of metabolic acidosis;
• Normalization of hemostasis;
• Correction of functions of all organs.

All medical measures for the onset of septic shock should be carried out simultaneously, rather than consistently.