Why kidney dysplasia develops and how dangerous it is for newborns

Kidney dysplasia is an anomaly in the formation of the genitourinary system in newborn infants. This is due to a decrease in the size of one or both of the kidneys, improper tissue formation and worsening of the urinary system.

Simple dysplasia is classified into two varieties, namely:

1. Rudimentary is a general defective kidney development when its size does not reach and 3 cm.
2. Dwarfish - the percentage of the presence of connective tissue in the kidney is much larger than the underlying tissue, insufficient sizes of its vessels, lack of nephrons, and the size is approximately 5 cm.

The polycystic form of renal dysplasia is isolated, when the formation of the kidney parenchyma is severely impaired, which provokes an increase in the formation of cysts.

This is important!

Kidney parenchyma dysplasia combines a whole group of pathologies that are independent or associated only with kidney failure or incorrect differentiation of their structures. Dysplasias can be clearly differentiated during the life of the patient due to the large spread of this diagnostic method, such as an intravital biopsy for the kidneys.

Existing varieties of pathology

Dysplasia with clinical and morphological characteristics:

1. Cystic dysplasia:
   • Polycystic pathology of adult and pediatric type, autosomal dominant and autosomal recessive.
   • Medullary form of cyst.
   • Microcystosis of the kidneys or congenital form of nephrotic syndrome.
   • Other varieties of cystosis.
2. Dysplasias without cysts:
   • Oligonemphronium.
   • Segmental form of hypoplasia.
3. Morphological hypoplastic dysplasia:
   • Dysplasias accompanied by metabolic disorders.
   • Dysplasia, supplemented with nephritis.

Why is this pathology manifested

? Dysplasia of the left or right kidney is considered an innate pathology and is formed even during intrauterine development of the fetus. Also, it can be formed after a certain time even after birth, when the effect of the factors causing a violation of the development of the fetus increases in time.

In addition, pathology can develop due to genetic disorders, but in about a third of cases of the disease the causes remain unsettled.

Manifestations of pathology

Every fifth variant of the course of the disease is an aplastic type and it is impossible to perform treatment if two kidneys are affected immediately. With the development of bilateral aplastic dysplasia, death, as a rule, occurs immediately after the birth of the child or even in the first days of his life.

Hypoplastic type of renal dysplasia worsens the functioning of the organ and in particular is the cause of their chronic insufficiency. In the process of diagnosis, doctors prefer to implement kidney biopsy, and the main manifestations of pathology include the following: high blood pressure, changes in the fundus, frequent convulsions, headaches and abdominal pain.

Symptoms of cystic dysplasia often correlate with signs of pyelonephritis or kidney failure. During the diagnosis, fluid neoplasms - cysts - are found. At the same time, the size of the organ increases and there is abdominal pain, body temperature rises, abundant and frequent vomiting and anemia. Bilateral kidney damage also leads to the death of the newborn.

This is important!

If we consider the overall development of a child with kidney dysplasia, then there is a development gap compared to their peers.

The dysplasia of the right or left kidney manifests itself depending on the condition of the second healthy organ. For the diagnosis is performed excretory urography, ultrasound examination, scintigraphy. In 20% of cases of renal dysplasia, the hypoplastic form is diagnosed, accompanied by a decrease in the size and mass of the injured organ.

In bilateral lesions, the clinical picture is characterized by signs of renal failure, and unilateral defeat provokes the manifestation of signs of pyelonephritis.

Multicystic kidney, as a rule, increases in size due to the presence of a number of cystic neoplasms in the tissue. Such pathology is only one-sided, since bilateral defeat leads to immediate death. With multicystic dysplasia, the pain syndrome is clearly pronounced, the arterial pressure is raised, and the kidney is lobate in nature.

Treatment of

pathology Treatment of kidney dysplasia can be classified into several varieties depending on the course of the disease:

• Symptomatic therapy.
• Treatment of glomerulonephritis, interstitial nephritis and pyelonephritis.
• Conservative and substitutive treatment of chronic form of renal failure.

A positive result allows you to achieve a previously performed nephrectomy - organ removal. Surgical intervention makes it possible to prevent the formation of a serious complication - a syndrome of increasing blood pressure indicators, accompanied by secondary disturbances in the functioning and structure of another kidney and the development of its deficiency.

This is important!

If you have symptoms of infectious disease of the urinary system in a child with kidney dysplasia, the use of antibiotic drugs is necessary. At the same time, isolated chemotherapy does not produce the expected result. Due to the fact that children with structural disorders of the formation of the kidney parenchyma are characterized by a violation of metabolic processes in the body, it is necessary to prescribe a salt-free diet.

Rapid progression of the syndrome of chronic kidney failure is mainly correlated with a congenital anomaly of the structure of the affected organ. Diagnosis of kidney dysplasia simultaneously with the presence of early signs of chronic organ failure in the child assumes an urgent decision about the treatment not only of drugs and hemodialysis, but also surgical operations for the implementation of transplantation of the affected kidney. The doctor should seriously approach the diagnosis of the disease and its nuances in order to organize the most appropriate treatment.

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