Cystic dysplasia of the kidney: for what reasons it develops and how dangerous it is

Cystic dysplasia of the kidney is a violation of the formation of the kidney parenchyma, which provokes the appearance of cystic neoplasms.

Polycystic in newborns and older children correlates with the categories of the most severe clinical cases. Kidneys are the organ that implements filtration in the human body and removes toxins from it, so improper functioning of the kidneys, provoked by polycystosis, can lead to death.

Used in modern medicine methods of conducting early diagnosis of the disease can establish the defeat of the kidneys even before the birth of the child. In this regard, the treatment of already diagnosed polycystosis can be carried out already in early childhood. The degree of damage to the kidneys depends on the treatment developed by the doctor - conservative therapy or surgical intervention.

If polycystosis has not been diagnosed in early childhood, then it begins to develop actively. In children, cystic neoplasms in the parenchyma can be very small, so do not cause any symptoms. But as you grow up, the number and size of cystic neoplasms increases, causing various deviations in the state of health.

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If polycystosis is found in the immediate family of a child, an immediate diagnosis is required. A timely diagnosis in children makes it possible to prevent the development of severe complications of the disease.

Most often, polycystic kidney dysplasia is a congenital pathology, but its first symptoms can appear already in an adult or even in old age. Most patients complain of a feeling of discomfort after twenty years. In medicine, cases are also known that the normal functioning of the kidneys in the presence of cysts persisted until the oldest person. But doctors can not predict the development of the disease precisely.

What provokes the development of the disease

The reasons for the formation of cysts in the kidney are primarily related to genetic factors. Specialists have discovered a special gene that can cause polycystosis. This gene is located in one of the non-sexual chromosomes, so children can inherit the disease regardless of their gender.

Polycystic can manifest itself even in early childhood. There are cases of diagnosing a disease in newborns, when a child suffers from kidney failure. Almost always polkistoz develops gradually, and the first signs can be found only after forty years. To this age in the parenchyma of the human kidney appears a lot of extensions, filled with liquid. It is believed that this condition is provoked by pathogenic development of the membrane of the tubules and glomeruli.

Symptoms of the disease

Symptoms of actively developing renal polycystic disease correlate with an increase in renal volume on both sides, the development of pain. In addition, a little later, there are characteristic complications, such as blood in the urine, the formation of kidney stones, increased blood pressure, inflammation in the organs of the urinary system. The most serious complication should be considered kidney failure, which has a chronic course.

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Enlargement of the kidneys in size can be detected when they are felt, when the patient complains of their soreness when pressing on the kidney zone. The main cause of pain is the stretching of the kidney parenchyma due to the increasing size of the cyst. The pain is localized in the lower back or in the side.

Methods of diagnosing the disease

Information from the patient's history allows to establish cases of polycystosis in the family, relatives of one line. The doctor does not always manage to find cystic changes in the kidneys, so preference is given to implementing the following diagnostic methods: ultrasound, excretory urography, computed tomography and MRI of kidneys, angiography, etc.

Due to intravenous urography, a strong bilateral increase in the size of the kidneys, as well as the deformation of the calyx and kidney loops. Ultrasound makes it possible to detect cystic neoplasms in enlarged ones. In doubtful situations, pyelography is organized, angiography of the kidneys, which allows to detect cystic lesions.

For the diagnosis of the level of compensatory renal function, urine tests and biochemical studies of blood tests are performed. With additional damage to pyelonephritis, a bacteriological culture of urine is carried out. Genetic examination of the kidneys is shown to reveal family types of the disease.

Polycystic kidney is required to be distinguished from other lesions, namely from chronic forms of pyelonephritis and glomerulonephritis, from a kidney tumor.

How is the treatment of polycystic kidney disease

? The most common treatment of polycystosis is symptomatic, that is, it involves the elimination of complications of the disease. With severe pain, the reception of pain medication is indicated, with the establishment of an infectious lesion it will be necessary to take antibacterial medications.

In the case of detection of large cystic lesions, strongly pressing on the tissue and causing severe impairment of kidney function, the organization of the operation is assigned. Urgent surgical intervention is performed with pronounced hematuria and strong renal colic.

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If one of the kidneys is severely damaged, it needs to be removed, but this operation can be realized only in situations where the twin kidney is able to at least partially fill in the functions of the removed kidney.

In the diagnosis of kidney failure, dialysis is indicated. Complete recovery becomes possible only when the patient is transplanted to a healthy organ.

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