How to reduce fibrinogen in pregnancy

If you mention fibrinogen, then it's about blood and its properties. Since childhood, it is known that blood can flow, and can stop. The most curious people always had a question - why?

During the waiting period of motherhood, women are interested in how to reduce fibrinogen during pregnancy and what is dangerous is an increase in its level.

Fibrinogen( the precursor of fibrin) is a protein from which the blood clot basically consists when it is clotted. According to the international nomenclature, it is the factor I( the first) of the plasma system that carries out blood clotting. The half-life of this component of blood is 100 hours. Fibrinogen is produced by the liver, from which it enters the blood together with other substances, where it is phased into thrombin in insoluble fibrin I( insoluble), resulting in a clot( according to the scheme: creation of fibrin-polymerization-stabilization-clot monomers).Its concentration in the blood determines the value of ESR - the rate of erythrocyte sedimentation directly depends on the concentration of fibrinogen. The degree of its concentration is also interrelated with the risk of cardiovascular complications. In this case, resort to measures that will reduce the level of cholesterol in the blood.

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Human fibrinogen

To study the content of fibrinogen, venous blood is taken, coagulogram( or hemostasiogram) is carried out - laboratory analysis for coagulation of blood. Before the beginning of the analysis( morning on an empty stomach), do not eat for 12 hours, for half an hour before the analysis should be in complete tranquility, do not smoke.

In prenatal diagnosis, this indicator is an important and necessary stage of it, it is always under control, as it signals possible inflammation and tissue death.

Please note! During pregnancy, the control and investigation of the level of fibrinogen in a woman's blood can be prescribed not only by a gynecologist, but also by a therapist, as well as specialists of a directed profile - cardiologist, hematologist, surgeon. Only they can reliably establish the cause of the change in the level of fibrinogen and prescribe a treatment that is safe for a woman with a child and is effective for fetal development.

Low fibrinogen

The level of fibrinogen in pregnant women is reduced quite rarely. This is due to toxicosis and the accompanying vomiting, which in the early stages of pregnancy can occur even up to 25 times a day. The reason for reducing the level of fibrinogen can also be DIC( disseminated intravascular coagulation), in which the body has already used up all its fibrinogen. With its deficiency, strong internal and external bleeding can be observed, which is difficult to stop. This is life-threatening, so this patient is closely involved in resuscitators. Calms only the fact that such borderline conditions in obstetrics are extremely rare. And if they do happen, timely taking the necessary measures is an extremely important condition.

Please note! This indicator decreases with toxicosis of pregnancy, poisoning with snake venom, liver diseases - cirrhosis, hepatitis, and also with a lack of vitamins( B12, C).Promotes the reduction of fibrinogen - fish oil. A decrease in the indicator is observed in the patient with a large amount of blood transfused to him or if mistakes were made in the blood transfusion.

High fibrinogen

Perhaps women are more often concerned about how to reduce fibrinogen in pregnancy if it is above normal.

With regard to increasing the level of fibrinogen in the blood of pregnant women, which is the norm within certain limits, it begins already for a period of three months. During pregnancy, an increase in the fibrinogen content in the blood plasma is observed physiologically, which, in particular, in the third trimester and immediately before birth reaches 6 g / l, which is quite acceptable( at a rate of 2-4 g / l in all other cases).The rate of fibrinogen in newborns is slightly lower - 1,25-3 g / l.

Too sharp increase, exceeding the maximum indicator of the level of fibrinogen - 6 grams per liter of blood - is an alarm signal. Hence, the organism of the future mother has been infected or a hotbed of inflammation has appeared.

Please note! "High" fibrinogen is a symptom of such diseases as influenza, pneumonia, tuberculosis, myocardial infarction, malignant tumors. It also accompanies burns, surgical interventions and even the administration of estrogens, contraceptives.

The result of the study on the level of fibrinogen in the blood is its reference values. Usually they should be temporary, since the concentration of fibrinogen in the blood has the property of returning to normal after the cessation of the effect on the body of undesirable factors. But if the impact of harmful factors does not stop on its own, it requires the help of qualified doctors and effective treatment.

The future mother, fulfilling all the requirements of a hematologist, obstetrician-gynecologist, achieves maximum protection from the risk of all sorts of severe complications. Modern medical achievements, the level of knowledge and skills help babies to be born even in the most desperate conditions, allow women during pregnancy to overcome all obstacles and become a happy mother.

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