Ichthyosis - Causes, symptoms and treatment. MF.

Ichthyosis is a disease with a hereditary predisposition, characterized by a violation of the cornification of the skin. There are 2 forms of ichthyosis - normal and X-linked.

Symptoms of ichthyosis

Ordinary ichthyosis is inherited autosomal dominantly. It develops not earlier than the first year of life. Among men and women ichthyosis occurs equally often. The disease is characterized by dryness and scaling of the skin, most pronounced on the extensor surface of the limbs. The folds are usually not affected. There is dryness of the palms and soles, with an underlined, reinforced pattern and deep grooves, which gives them a senile appearance. Nails are not involved in the process and remain unchanged. Many have signs of atopy( increased tendency to allergies).With age, the course of the disease improves somewhat.

X-linked ichthyosis is inherited recessively, hence the disease is observed only in boys. Unlike ordinary ichthyosis, it can exist from birth, scales larger, brownish in color;the folds, neck, and the rear are affected, but there are no changes on the palms and soles;The process is more pronounced on the flexural surface of the extremities and on the abdomen;there may be considerable peeling on the scalp. Often, there is opacity of the cornea, as well as hypogonadism( underdevelopment of genital organs and secondary sexual characteristics due to decreased secretion of sex hormones.), Cryptorchidism( absence of monochromism in one of the scrotums or both testicles, which is due to retardation of embryo development).

Treatment and prevention of ichthyosis

The main means of general therapy of ichthyosis is vitamin A, prescribed in large doses, for 2-3 months, repeated cycles( 2-3 times per year), tigazone. It is recommended to combine vitamin A with tocopherol acetate( especially Aevit).Osablennymi people are prescribed fortifying agents( iron preparations, fitin, etc.), y-globulin, anabolic steroids( retabolil).The appointment of vitamin B12 is shown. Thyroidine is recommended, it is given by 5-day cycles with 2-3-day intervals during the month.

Frequent warm( 38. .. 39 ° С) baths are better, with the addition of drinking soda( 50-100 g), milk( 0.5 l), olive oil( 1-2 tablespoons), table salt( 100-200 g).After that, the skin must be lubricated with moisturizing and nourishing ointments( creams), cream with vitamins, for example.radevit, f-99;creams containing 0.5-2% salicylic acid( because of the risk of intoxication, this ointment can not be applied to large areas of the body, especially in children), cream with 5-10% urea;ultraviolet irradiation.