Number of red blood cells

The number of red blood cells in the blood( RBC) is one of the most important indicators of the blood system. Erythrocyte is the most numerous blood element that contains Hb. It is formed from the reticulocyte upon its exit from the red bone marrow, the final transformation of the reticulocyte into a mature red blood cell takes place within a few hours. The erythrocyte has the shape of a biconcave disk, which provides the maximum "surface area / volume ratio".The diameter of the mature erythrocyte is 7-8 microns( deviations in the range from 5.89 to 9.13 microns - physiological anisocytosis).Reference values ​​of the number of erythrocytes in the blood are presented in Table.[Titz N., 1997].

Reducing the number of red blood cells in the blood is one of the criteria for anemia. The degree of erythrocytopenia varies widely among different anemia. With iron deficiency anemia on the basis of chronic blood loss, the number of red blood cells can be normal or reduced moderately - 3-3.6 x 1012 / l. In case of acute blood loss, B12-deficiency anemia, gipoplastic anemia, hemolytic anemia after hemolytic crisis, the amount of red blood cells in the blood can decrease to 1-1,6х1012 / l, which is considered an indication for urgent medical measures.

The number of red blood cells , in addition to anemia, decreases with an increase in the volume of circulating blood - pregnancy, hyperproteinemia, hyperhydration.

An increase in the number of erythrocytes in the blood-erythrocytosis( more than 6x1012 / L in men and 5x1012 / L in women-is one of the characteristic laboratory signs of erythremia.) Erythrocytosis can be absolute( increase in the mass of circulating erythrocytes, due to erythro-poetry) and relativevolume of circulating

blood.) The main reasons for the increase in the number of red blood cells in the blood are presented in the table.

Table Reference values ​​of the number of red blood cells in the blood

Table Diseases and conditions,awaiting an increase in the number of red blood cells in the blood

Table Diseases and conditions accompanied by an increase in the number of red blood cells in the blood