How does kidney hypoplasia manifest, how to detect and treat it

Hypoplasia of the kidney, as a rule, is manifested due to the improper development of this body in the embryonic period. Such an organ looks absolutely normal, but only has smaller dimensions.

Unilateral pathology can occur without clinical manifestations, but often in the abnormal kidney develops pyelonephritis, which triggers the onset of hypertension in the kidney. Heavy forms of bilateral defeat early make themselves known - in the first year or even in the first weeks of the life of the child. Against this background, physical underdevelopment is formed in children.

Causes of pathology

The main causes of kidney hypoplasia are insufficient blastema mass with the simultaneous proper functioning of the methanephros flow. In this regard, nephrons are characterized by a normal structure and can work correctly, but their number is only half of normal. The opposite kidney usually makes up for the lack of nephrons, so, in sum, the function remains normal.

In medicine, there is an opinion that kidney hypoplasia, like any other hypoplasia - is a defect that is formed even during intrauterine development. Inadequate intrauterine growth of the body closely correlates with internal and external factors that affect the body of a woman in the situation.

Hypoplasia often becomes a genetic abnormality, and it can also be caused by the following etiological factors:

• Primary underdevelopment, which correlates with a person's hereditary predisposition.
• Pyelonephritis, which develops in utero, or in a child under one year old.
• Secondary process of inflammation in the kidneys, which become very vulnerable in the sense of the development of inflammation in their interstitial tissues.
• Intrauterine blockage of veins in the kidneys, which provokes the underdevelopment of this organ.
• Malnutrition during pregnancy and insufficient amount of amniotic fluid.
• Abnormal arrangement of the fetus. Infectious pathology in the mother - rubella, influenza, etc.

Manifestations of pathology

If the lesion is one-sided, and the only healthy kidney functions correctly, the signs of hypoplasia may not appear throughout the life of a person. If the functions of a healthy kidney are violated, the second reduced one can undergo an inflammatory process, be affected by pyelonephritis with a typical clinic characteristic of this disease.

Often, kidney hypoplasia can trigger the development of persistent hypertension in a child. Chronic hypertension in the kidneys often becomes an excuse for removing a reduced organ, since this process does not lend itself to drug therapy and can acquire a malignant course.

The inadequate development of an organ can manifest itself more actively regarding the clinical symptomatology:

• A serious lag in the child's mental and physical development.
• Skin blurred, swelling of the face and limbs.
• Chronic diarrhea.
• Increased body temperature to 37 - 38 degrees.
• Manifestations resembling the signs of rickets, namely - softening of bone tissue, dark protruding cranial bumps, curvature of the legs, flattening of the occiput, hair loss and bloating.
• Chronic kidney failure.
• Increased blood pressure.
• Frequent nausea sometimes with vomiting.

Bilateral renal disease is characterized by an unfavorable prognosis for children under one year, as both organs can not function properly and can not yet undergo transplantation.

One-sided lesion is occasionally characterized by specific signs and is diagnosed quite accidentally during a medical check-up or during a comprehensive examination due to the development of another disease.

Hypoplasia of the right kidney is almost indistinguishable from left hypoplasia. This concerns clinical symptoms and functioning. Hypoplasia of the right kidney can be detected randomly or with intrauterine development, as well as during a primary examination of the newborn.

According to the anatomical structure, the left kidney is somewhat higher than the right kidney, so the left kidneys hypoplasia manifests itself with more vivid clinical symptoms.

Diagnosis of pathology

Differential diagnosis of hypoplasia is performed with dysplasia in the kidney and with a wrinkled kidney. Proof of the pathological process is the correct structure of the vessels in the kidney, the bowl-pelvic system, the ureter. To identify these signs, it is sufficient to organize an MRI, which, if necessary, is combined with dynamic nephroscintigraphy. Clinically, with such a defect, much attention is paid to the condition of the contralateral kidney, since trauma or the development of pathology in it can cause insufficiency.

Hypoplasia of the kidney is characterized by an insufficient size of this organ with simultaneous general underdevelopment of the structure of the kidney, its vessels. Such an anomaly can be two-sided. Clinically, most often this defect is manifested by increased blood pressure and signs of chronic form of pyelonephritis

Symptomatic is often characterized by arterial hypertension and manifestations of chronic pyelonephritis in connection with the structure of the vasculature within the organ, trunk vessels, cups and pelvis in the kidney.

Therapeutic process of pathology

The underdevelopment of one of the kidneys or both kidneys is a complex deviation, and due to late diagnosis it is difficult to treat. Treatment of kidney hypoplasia involves a variational approach, which depends on the type of hypoplasia and on the functioning of a normally functioning kidney.

If the deviation of kidney development is detected in early childhood and diagnosed by bilateral lesion, attempts may be made to restore and change the water-electrolyte balance and neutralize the intoxication of blood flow through nitrogenous products. With pronounced hypoplasia of both kidneys, the child mostly dies from heart failure and uremia. Forecasts remain unfavorable and children with such a defeat survive only up to 8-15 years.

Tactics of the therapeutic process of a one-sided lesion are developed taking into account individual characteristics in the patient's state of health. In general, therapeutic manipulations are similar to those that are organized for patients with a single kidney.

Removal of a reduced kidney is usually necessary for patients aged, because a reduced kidney in children is able to function. At least 30% of the norm. Patients need regular check-ups, constant supervision, examinations at the doctor and symptomatic therapy in detecting suspicions, even for the slightest deviations in the work of the body.

When diagnosing a severe bilateral lesion, surgical intervention is required and, as a rule, two abnormal kidneys are removed. In this case, the patient is transferred to hemodialysis and organ transplantation is organized for him.