What is dysbiosis?

The ratio of different populations of microbes that support the biochemical, immunological equilibrium and normal metabolism in the human body, necessary for maintaining and maintaining health, is called normoflora. Disbacteriosis( dysbiosis) is a qualitative and( or) quantitative violation of this relationship with the subsequent development of metabolic and immunity disorders and the possible occurrence of intestinal and gastric disorders.

This is primarily expressed in:

a decrease in the concentration of bifidobacteria by 1-2 orders of magnitude;

reduced the concentration of lactobacilli by 1-2 orders of magnitude;

increase in the concentration of E. coli with altered properties;

decrease or increase in the concentration of normal E. coli;

increase in the concentration of other opportunistic microorganisms.

There are a large number of factors, both external and internal, which violate the biological balance of normoflora. And their specificity largely depends on age.

1. Newborns:

bacterial vaginosis and mastitis in the mother;

carrying out resuscitation measures for a newborn;

later applying to the breast;

long stay in the maternity hospital and the possibility of colon colonization with aggressive strains of environmental microorganisms;

physiological immaturity of intestinal motor function;

presence of small purulent infections;

breast milk intolerance;

primary immunodeficiency.

2. Breast and early age:

unfavorable during the neonatal period( in history);

early infant feeding;

dyspeptic disorders;

frequent acute respiratory viral infections;

rickets;

anemia;

of hypotrophy;

changes in the psychoneurological status of the child;

allergic dermatitis.

3. Preschool and school age:

being in closed collectives;

frequent acute respiratory viral infections;

allergic reactions.

4. Juvenile:

frequent acute respiratory infections;

allergic reactions;

addiction.

5. Average age:

occupational hazards.

6. Elderly:

age-related changes in microflora properties.

7. Regardless of age:

stress;

an unbalanced diet( non-nutritional diet, a set of foods and low quality);

intestinal infections;

treatment with antibacterial drugs;

long-term hormonotherapy, treatment with non-steroidal anti-inflammatory drugs;

chemotherapy and radiation therapy in cancer patients;

immunodeficiency states.

Dysbacteriosis is diagnosed on the basis of clinical examination and microbiological analysis of stool.

The main manifestations of intestinal dysbacteriosis: a violation of the general condition( intoxication, dehydration), weight loss, symptoms of gastrointestinal mucosal lesions and digestive disorders in various parts of it.