The value of total bilirubin in the diagnosis of diseases

In the human body, hemoglobin, cytochromes and myoglobin are found in a strict combination, which must disintegrate in a certain way in the cells of the liver, spleen, releasing a yellow color dye, the main component of bile. If this process is not violated, the hematopoietic serum will contain a component of bilirubin. It is two different fractions of the pigmenting substance. Together, they represent the common bilirubin of a fluid mobile internal tissue of red color.

At laboratory researches of structure of a blood the general and direct bilirubin( a pigment) are allocated. A difference appears between the indications of these components, that is, a free pigmenting agent.

The initial product of the breakdown of hemoglobin is free bilirubin, a toxic, water insoluble, but easily lipid soluble membrane. The increased content of bilirubin causes a disease that is accompanied by yellowing of the skin. The withdrawal of this pigment from the body is carried out by the work of the liver. Yellowness indicates a blood disease.

Thus, bilirubin is the main pigment of bile in the human body, formed from obsolete cells of erythrocytes and rendered harmless in the liver. In this form, it is easily removed from the human body.

Reduced bilirubin content

Quantitative deviation of the bile pigment content from the norm signals a malaise. Human blood is a complex mix of different structures, plasma, cells, white and red plates, and bodies. In the normal state, it contains an unequal number of pigment material, depending on various circumstances( daytime, ill health, race, etc.).

At night there is a gradual increase in the level of this enzyme in the blood flow, and in the daytime the indicator decreases.

Various diseases affect the red body content, lowering their level, so bilirubin decreases. Medical practice, diagnostics identified diseases - a chronic nature associated with the kidneys, lungs caused by Koch chopsticks, thinness - accompanied by a drop in the dye.

It is noted that total bilirubin is lower in women than in men, in children it differs from that of adults. In addition, the amount of pigment is affected by racial signs, that is, people of European origin have a slightly higher bilirubin level than those from the African continent.

There are prerequisites that the common bilirubin is directly related to the oxidative activity of the body. Increased oxidative activity leads to an overabundance of endogenous antioxidants. Coronary heart disease in retired people is very often in some accordance with a decrease in the amount of pigment of bile.

The norm of bilirubin

Hence, there must be some norm of the content of bile pigment in the human body. Violation of this proportion often indicates the process in the human body caused by pathogenic viruses or other cause of ill health. Our internal organs are easily exposed to unfavorable conditions of feeding, breathing, surrounding the aggressive environment.

To determine the cause, a blood test for bilirubin is performed. With the help of laboratory methods, the internal state, the functioning of the entire secretory system, the exchange between organs, the requests for a lack of trace elements are determined.

Biochemical study is important for identifying the causes of almost all disease states, so it is suggested to pass a laboratory test, to make detailed analyzes.

Results with elevated figures of total bilirubin indicate a poor condition in the hepatic cells, a violation of the biliary function associated with the removal of the enzyme.

Now there are different methods of diagnosis, so different clinics produce different results, different units of measurement. Correct decoding of the result of a biochemical blood test can be done by the attending physician.

General bilirubin in the blood

To diagnose and monitor the course of treatment of diseases of the blood, liver and bile excretion routes, it is possible to predict the course of chronic liver diseases using blood tests. Thus, the total bilirubin in the blood, determining its level is important for diagnosing chronic diseases.

The results of the tests can be affected by physical exercises, and the effect is expressed in increasing the measurement parameters. Increase the level of certain medications( barbiturates containing caffeine, antibiotics, paracetamol and salicylic acid).

If at the next visit to the doctor receives a referral for a survey of the blood content of bilirubin, then there was a premise from medical positions to trouble with internal organs. This may be a simple lack of vitamin B12, but you should be prepared for more serious deviations. Even an ordinary drug overdose provokes a malfunction in the working rhythm of the body.

Special attention is paid to newborns. According to the color of their delicate skin, the doctor determines the cause visually. And often timely irradiation with ultraviolet solves the maturing problem at the very embryo, the child does not have to be treated with strong drugs.

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