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Kidney anagenesis, its treatment and subsequent life with a single kidney

  • Kidney anagenesis, its treatment and subsequent life with a single kidney

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    Kidney agenesis is a pathology of organ formation during intrauterine development, when one or two kidneys are missing at once. At the same time, other kidney structures remain unformed. In this case the ureter can be developed almost normally or absent altogether. Aging is a common developmental disorder, and life with one kidney due to adequate medical actions can remain full.

    Reliable information that agenesis is a hereditary genetic disease is missing. Often, the cause of pathology are numerous malformations of the fetus due to the influence of exogenous factors on it during pregnancy of a woman.

    Simultaneously with the fact that the child has only one congenital kidney, there are other anomalies in the structure of the genitourinary system. The ureter and the vas deferens on the affected side may also be absent. Girls with agenesis are diagnosed with malformation of the reproductive system. The risk of manifestation in newborn agenesis can be attributed to factors such as diabetes mellitus.

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    Causes of the disease

    The preconditions that a child has a single kidney at birth are laid even in the early stages of intrauterine development - when the organs of a future child are formed.

    It has been established that the risks of childbirth with agenesis are markedly increased in those mothers who are ill with diabetes mellitus. In addition, agenesis can be triggered by a stroke in the developing ureteric bud or other teratogenic factors.

    Symptoms of the disease

    In the formation of unilateral agenesis in a newborn, as a rule, there is no ureter. Pain can develop in the inguinal zone, in the sacrum, as well as the violation of the structure of the organs of the reproductive system.

    If a child was born with a single kidney, it usually has an unhealthy appearance, namely: deformed ears, a prominent forehead protruding, a flat and wide nose, puffiness and a puffiness of the face. With such anomalies in the structure of the kidneys, children are usually premature, a healthy kidney increases in size, since it realizes compensatory functions.

    Species of the disease

    Bilateral renal agenesis is considered the third clinical type. In this case, newborn babies are most often dead at birth. But there were cases when children were born full-blooded and alive, but already in the first days of life they died because of severe insufficiency. Currently, medicine does not stand still and is constantly being improved, so there is a possibility of a technical organ transplant to a newborn child and the organization of a subsequent hemodialysis. It is very important to timely differentiate the bilateral form of agenesis with other anomalies in the formation of the urinary channels.

    One-sided form of renal agenesis is considered the first clinical type of pathology and can be congenital. In the absence of one kidney, all the functional load is taken by a healthy kidney, which often increases in size due to substitution work. The increase in the number of structural elements in a healthy kidney allows the body to realize the work of two normal ones. But the risk of serious complications in case of trauma to this kidney is greatly increased.

    Unilateral form of agenesis, accompanied by the absence of the ureter - the main sign of this developmental anomaly is the absence of the ureteral mouth. Due to the peculiarities of the structure of the body, men agenesis in males is combined with the absence of a duct through which the seminal fluid is excreted, as well as with some changes in the structure of seminal vesicles. Such deviations in development provoke pain in the groin, sacrum, pain during ejaculation and violations of the sexual function of men.

    Diagnosis of an anomaly

    Diagnosis of renal agenesis is usually determined by CT, urography, ultrasound, provided that the newborn has a flat and broad nose, low-lying and somewhat deformed ears, a puffy face, strongly protruding frontal lobes, an increased distancebetween the eyes, insufficient size of the upper jaw. Sometimes there is a strong folding of the skin, deforming the lower limbs, reducing the size of the lungs and increasing the volume of the stomach.

    If a child has one kidney in the norm, then almost any manifestations of this disease are almost absent and they reveal him completely by accident. The bilateral form of agenesis is complemented by polyuria, increased blood pressure and kidney failure.

    In the first days of a child's life, any form of agenesis is manifested through vomiting, dehydration, increased blood pressure, polyuria and kidney failure.

    Usually, agenesis is diagnosed with cystoscopy, excretory urography, and angiography.

    Treatment of the disease

    The development of the disease in newborns causes a huge risk to life. Currently, there are two types of renal agenesis treatment, namely antibacterial treatment and surgical intervention, that is, a donor kidney transplant. Often doctors come to carry out surgery, because organ transplantation is the most effective method of treatment, despite the high risks for the health and life of the child.

    In the successful treatment of renal agenesis, children have chances of further life in the future.

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