The stability of the collagen matrix is ​​provided by intermolecular irreversible bonds formed between some amino acids entering the polypeptide chain of collagen. Due to the presence of the p...

Sodium uretic peptides are important in regulating the volume of sodium and water. The first was the atrial natriuretic peptide( ANP), or the atrial natriuretic peptide type A. The ANP peptide ...

Reference values ​​of concentration of C-peptide in serum in adults - 0,78-1,89 ng / ml. The C-peptide is a fragment of the proinsulin molecule, resulting in the cleavage of which insulin ...

Reference values ​​of serotonin concentration in serum in adults - 0,22-2,05 μmol / l( 40-80 mkg / l);in whole blood - 0.281.14 μmol / l( 50-200 ng / ml). Serotonin( oxytryptamine) is a biogeni...

The wide use of various restriction endonucleases for the analysis of chromosomal DNA revealed a huge variability in the human genome. Even small changes in the coding and regulatory regions o...

Prenatal diagnosis is the most effective method of preventing congenital diseases. It allows in many cases to unequivocally solve the problem of possible damage to the fetus and the subsequent te...

Monogenic defects( determined by one gene) are observed more often than chromosomal defects. Diagnosis of diseases usually begins with the analysis of clinical and biochemical data, the pedigr...

Disturbance of lipid metabolism can occur at the level of their splitting, absorption, transport, and intermediate metabolism. There are two main types of hereditary disturbances in the metabo...

Three main components of connective tissue are distinguished: ■ cellular elements; ■ collagen, elastic and reticular fibers; ■ amorphous basic substance. Genetic defects in the s...

The development of each individual is the result of the interaction of genetic and external factors. A set of human genes is established during fertilization and then, together with environmental...

Thalassemia is a heterogeneous group of genetic disorders associated with impaired synthesis of normal Hb polypeptide chains. These anomalies lead to the development of hypochromic microcytic ane...

Carbon monoxide( CO, carbon monoxide, carbon monoxide) is a gas without color, taste and smell, which does not cause irritation, an incomplete combustion product. It is a part of many industri...

Ethyl alcohol( ethanol , C2H5OH) has a sedative-hypnotic effect. When ingested, ethanol, as well as methanol, ethylene glycol and other alcohols, is easily absorbed from the stomach( 20%) and th...

Primary immunodeficiencies arise as a result of genetic disorders in the development and maturation of cells of the immune system, which increases the sensitivity of the organism to infections. ...

The most typical changes with aging are lipid metabolism. The concentration of lipids and LP in the serum reflects a predisposition to the development of atherosclerosis and cardiovascular ...

Opioids refer to substances that cause physical and psychological dependence. Opium is produced from opium poppy juice( Papaver somniferum), it contains more than 20 different alkaloids, th...

The pituitary-adrenal system plays an important role in the overall adaptive response of the body, including in ensuring resistance to stress, maintaining ion homeostasis and regulating the im...

In order to ascertain with certain certainty the predominant role of one or several mechanisms, the intervention of additional factors in the natural development of the aging process, it is ne...