Why is it necessary to check basophils in children in the blood?

Basophils in children, as well as in adults, carry out the immune response of the body to the introduction of foreign organisms or substances. This insignificant group of leukocyte cells of white blood makes up only about 1% of their total number.

They were found and described as early as the 19th century, as a specific variant of mast cells. Modern science has revised this issue, and now it is believed that these are two different elements, although they have similarities in structure and functional activity.

Basophils include a large number of mediators of inflammation, and when they introduce a pathogenic microorganism or foreign substance, they are the first to appear on this site, secrete serotonin, histamine, and other substances, provoking an inflammatory reaction and attracting other types of leukocytes, which complete the work on the immune response. Despite their fairly short life, these elements are very important for the normal functioning of the body.

The number of basophils is normal in a child

At the moment, for any disease and examinations for the purpose of prevention, a blood test is prescribed. This helps in determining the hidden pathology and enables the doctor to clarify the diagnosis. Identifying the level of basophils also provides an invaluable service for understanding the current ailment.

In order to determine basophilic granulocytes, it is necessary to donate blood with an obligatory leukocyte formula. Normal indicators for a newborn is the number of these cells within 0.75 × 109 / l. When the baby turns month, a decrease to 0.5 × 109 / l is detected, and by one year the figure again comes to the previous value, about 0.7 × 109 / l.

What is needed for basophils

In the body of any person, including children, it is necessary to maintain normal life. Each component of the blood has its own meaning, and performs certain functions. There are also tasks for basophils:

• maintenance of normal blood flow;
• assistance in the formation of new capillary meshes;
• redirection to the tissues of other representatives of the leukocyte formula;
• intestinal protection;
• is active in the formation of allergic reactions of any type( both immediate and delayed);
• normalization of trophic tissue processes;
• activation of the inflammation process.

A change in the normal basophil counts in a baby's blood can indicate serious health problems. Therefore, parents should know that if there is even a slight increase or decrease, it is necessary to immediately pay attention to this pediatrician, and if there is such a need, then consult with other specialists.

Increase in basophils in the blood

Basophils are elevated in the child can be for various reasons, so when you get this result, according to clinical symptoms, you can assume the following:

1. A generalized form of an allergic reaction to any kind of food or medications.
2. Infection with worms.
3. Infectious diseases( chicken pox).
4. Radioactive Emission.
5. Reaction to an insect bite.
6. Poisoning.
7. Iron deficiency anemia.
8. Diseases of the blood( Hodgkin's disease, myeloleukemia, acute leukemia, polycythemia).
9. Disruption of the thyroid gland.
10. Renal pathology.

It is thanks to the rapid reaction of basophils that the outbreak is limited by the bites of animals and poisonous insects, they help localize the zone into which the poison enters and does not allow it to spread throughout the body.

Basopenia in a child

There are cases of a decrease in basophils in a child. In this case, you should immediately go to the doctor, as this may indicate the presence of severe endocrine pathology, or a malfunction of the bone marrow.

A condition in which the number of basophils in the blood is reduced is called basobenia specialists. It can be observed during:

1. stress;
2. development of acute infection;
3. use of hormonal drugs;
4. Cushing's Disease.

Sometimes there are options for analyzing the blood in a baby, in which these elements are not determined. To check the condition of the child in case of basbopenia, it is necessary to consult a hematologist, an endocrinologist, an infectious disease specialist.

Treatment and prevention of

Any treatment at home without the involvement of professionals can lead to very negative results. Based on the data of the developed blood formula, the doctor will conduct the child's examination, and will appoint additional studies and treatment. If necessary, he will recommend the passage of other specialists.

Basophilia or basepenia are subject to elimination of their cause. If the results indicate the absence of pathological processes in the body, then one should think that changes in the number of basophils can be caused by deficient states. It is well known that a decrease in the blood of iron can often cause an increase in the level of these blood cells.

Assigning sufficient doses of iron-containing drugs and adjusting the diet will help to eliminate this phenomenon.

To bring the level to normal, the use of cyanocobalamin, or vitamin B12, is also recommended. It has a very beneficial effect on the formation of blood cells and is also able to bring the basophilic granulocyte count to normal.

If violations in the blood are caused by the methods of certain medicines, then in order to normalize the picture of the blood, it is enough to cancel them.

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